Amit Khatri Selected Research

Interleukin-17 (Interleukin 17)

1/2019	Pharmacokinetics, Safety, and Tolerability of the Dual Inhibitor of Tumor Necrosis Factor-α and Interleukin 17A, ABBV-257, in Healthy Volunteers and Patients With Rheumatoid Arthritis.
1/2019	Exposure-response analyses demonstrate no evidence of interleukin 17A contribution to efficacy of ABT-122 in rheumatoid or psoriatic arthritis.
11/2018	ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study.
11/2018	Dual inhibition of tumour necrosis factor and interleukin-17A with ABT-122: open-label long-term extension studies in rheumatoid arthritis or psoriatic arthritis.
11/2018	Phase II Study of ABT-122, a Tumor Necrosis Factor- and Interleukin-17A-Targeted Dual Variable Domain Immunoglobulin, in Patients With Psoriatic Arthritis With an Inadequate Response to Methotrexate.
1/2018	Population Pharmacokinetics of the TNF-α and IL-17A Dual-Variable Domain Antibody ABT-122 in Healthy Volunteers and Subjects With Psoriatic or Rheumatoid Arthritis: Analysis of Phase 1 and 2 Clinical Trials.
12/2017	Safety, Tolerability, and Pharmacodynamics of ABT-122, a Tumor Necrosis Factor- and Interleukin-17-Targeted Dual Variable Domain Immunoglobulin, in Patients With Rheumatoid Arthritis.

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Amit Khatri Research Topics

Disease

25	Infections 01/2020 - 01/2014
9	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020 - 11/2018
7	Body Weight (Weight, Body) 12/2019 - 01/2014
7	Fibrosis (Cirrhosis) 01/2017 - 12/2012
6	Rheumatoid Arthritis 01/2019 - 12/2017
5	Psoriatic Arthritis 01/2019 - 01/2018
5	Chronic Hepatitis C 01/2017 - 07/2015
4	Hepatitis C 01/2017 - 03/2015
3	Hypersensitivity (Allergy) 11/2018 - 12/2017
3	Coinfection 01/2017 - 03/2015
3	Neoplasms (Cancer) 07/2012 - 09/2011
2	Chronic Kidney Failure (Chronic Renal Failure) 02/2019 - 06/2016
2	Chronic Renal Insufficiency 02/2019 - 06/2016
2	Edema (Dropsy) 01/2016 - 12/2011
1	Dental Caries (Decay, Dental) 01/2024
1	Recurrent respiratory papillomatosis 01/2024
1	Benign Migratory Glossitis (Geographic Tongue) 01/2024
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 12/2023
1	Lipodystrophy 12/2023
1	Autistic Disorder (Autism) 04/2023
1	Postoperative Pain 03/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Endocarditis 01/2020
1	Bacteremia 01/2020
1	Nasal Obstruction 07/2019
1	Pain (Aches) 04/2019
1	Hypesthesia (Numbness) 04/2019
1	Crohn Disease (Crohn's Disease) 01/2019
1	Necrosis 11/2018
1	Inflammation (Inflammations) 12/2017
1	Malocclusion (Crossbite) 05/2017
1	Wounds and Injuries (Trauma) 04/2017
1	Pneumonia (Pneumonitis) 04/2017
1	Viremia 01/2017
1	Anemia 06/2016
1	HIV Infections (HIV Infection) 04/2016

Drug/Important Bio-Agent (IBA)

22	paritaprevirIBA 02/2019 - 01/2014
19	Ritonavir (Norvir)FDA Link 02/2019 - 01/2014
19	ombitasvirIBA 02/2019 - 01/2014
19	Antiviral Agents (Antivirals)IBA 10/2017 - 01/2014
17	dasabuvirIBA 02/2019 - 01/2014
9	Ribavirin (Virazole)FDA LinkGeneric 02/2019 - 01/2014
8	risankizumabIBA 01/2020 - 01/2019
7	Interleukin-17 (Interleukin 17)IBA 01/2019 - 12/2017
6	ABT-122IBA 01/2019 - 12/2017
4	CreatinineIBA 01/2020 - 01/2016
4	Monoclonal AntibodiesIBA 01/2020 - 10/2019
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 12/2017
4	Protease Inhibitors (Protease Inhibitor)IBA 10/2017 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 12/2023 - 10/2017
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2020 - 01/2016
3	Interleukin-23 (Interleukin 23)IBA 01/2020 - 01/2019
3	Methotrexate (Mexate)FDA LinkGeneric 11/2018 - 01/2018
3	InterferonsIBA 01/2017 - 01/2014
3	Gemcitabine FDA Link 07/2012 - 12/2011
2	C-Reactive ProteinIBA 01/2020 - 11/2018
2	Darunavir (Prezista)FDA Link 01/2017 - 01/2017
2	BilirubinIBA 01/2016 - 01/2014
2	RNA (Ribonucleic Acid)IBA 03/2015 - 01/2014
2	Atazanavir Sulfate (Reyataz)FDA Link 03/2015 - 01/2014
2	Raltegravir Potassium FDA Link 03/2015 - 01/2014
1	Bevacizumab (Avastin)FDA Link 01/2024
1	Angiogenesis InhibitorsIBA 01/2024
1	Adalimumab (Humira)FDA Link 01/2020
1	AntibodiesIBA 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Serum AlbuminIBA 01/2020
1	InterleukinsIBA 10/2019
1	Metoprolol (Toprol-XL)FDA LinkGeneric 01/2019
1	Midazolam (Versed)FDA LinkGeneric 01/2019
1	Warfarin (Coumadin)FDA LinkGeneric 01/2019
1	Cytochrome P-450 CYP3AIBA 01/2019
1	AlbuminsIBA 01/2019
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2019
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 01/2019
1	EnzymesIBA 01/2019
1	Omeprazole (Prilosec)FDA LinkGeneric 01/2019
1	Cytochrome P-450 CYP2C19IBA 01/2019
1	Caffeine (No Doz)FDA LinkGeneric 01/2019
1	Cytochrome P-450 CYP2C9IBA 01/2019
1	amsonic acid (DAS)IBA 11/2018
1	ChemokinesIBA 12/2017
1	NucleosidesIBA 10/2017
1	Dihydrotachysterol (AT 10)IBA 04/2017
1	Glucose (Dextrose)FDA LinkGeneric 04/2017
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2017
1	TabletsIBA 01/2017
1	Opioid Analgesics (Opioids)IBA 01/2017
1	Erythropoietin FDA Link 06/2016
1	Human immunodeficiency virus 1 p16 proteaseIBA 04/2016

Therapy/Procedure

9	Therapeutics 01/2024 - 07/2012
2	Splints (Splint) 05/2017 - 11/2011
1	Oral Diagnosis (Oral Examination) 01/2024
1	Animal Assisted Therapy 04/2023
1	Pulpectomy 03/2021
1	Antibiotic Prophylaxis 01/2020
1	Stents 07/2019
1	Anesthesia 04/2019
1	Functional Orthodontic Appliances (Herbst Appliance) 05/2017
1	Renal Dialysis (Hemodialysis) 06/2016